Ricardo Mostany, Assistant Professor of Pharmacology, was born in Palencia, a city of about eighty thousand people in the North of Spain. He obtained his BS in Biology from the University of Leon where he also pursued a PhD in Neurobiology. After his graduation he moved to the North coast as a postdoctoral trainee in the department of Physiology and Pharmacology at the Universidad de Cantabria in Santander. Ricardo continued his postdoctoral training in the department of Neurology at the University of California, Los Angeles. He joined Tulane in 2012.
His laboratory utilizes cutting edge imaging techniques to study how the aging brain handles and stores the information that receives from the environment. He thinks that the aged brain is not able to maintain the contacts between brain cells, the synapses, long enough to form long-lasting memories. This inability of maintaining the synapses between brain cells may be the reason why the aging brain shows deficits learning and remembering. To investigate these age-related deficits in neuronal connectivity, Mostany has recently received (September 2016) a $1.5M grant from the National Institutes of Health/National Institute on Aging.
Another chapter of Mostany’s research focuses on the study of the age-related differential vulnerability of certain neuron subtypes during stroke to find ways to protect the brain from ischemic damage and minimize the severity of the stroke, and improve functional outcome. Ricardo believes that identifying and protecting the neurons that appear to be more vulnerable to ischemia will help in the design of therapeutic approaches to improve the quality of life of the elderly and of those recovering after stroke.
Ricardo Mostany was awarded the Tulane University Oliver Fund Scholars Award in 2016.
Understanding the mechanisms dictating synaptic plasticity in the healthy brain to apply the knowledge to the study of aging, neurodegenerative diseases, and brain injury.
Re-endothelialization of rat lung scaffolds through passive, gravity-driven seeding of segment-specific pulmonary endothelial cells. Scarritt ME, Pashos NC, Motherwell JM, Eagle ZR, Burkett BJ, Gregory AN, Mostany R, Weiss DJ, Alvarez DF, Bunnell BA
Analysis of cardiovascular responses to the H2S donors Na2S and NaHS in the rat. Yoo D, Jupiter RC, Pankey EA, Reddy VG, Edward JA, Swan KW, Peak TC, Mostany R, Kadowitz PJ. Am J Physiol Heart Circ Physiol. 2015 Aug 15;309(4):H605-14. doi: 10.1152/ajpheart.00171.2015. Epub 2015 Jun 12.
Layer 4 pyramidal neurons exhibit robust dendritic spine plasticity in vivo after input deprivation. Miquelajauregui A, Kribakaran S, Mostany R, Badaloni A, Consalez GG, Portera-Cailliau C.J Neurosci. 2015 May 6;35(18):7287-94. doi: 10.1523/JNEUROSCI.5215-14.2015.
Two-photon excitation microscopy and its applications in neuroscience. Mostany R, Miquelajauregui A, Shtrahman M, Portera-Cailliau C.Methods Mol Biol. 2015;1251:25-42. doi: 10.1007/978-1-4939-2080-8_2.
Full List of Dr. Mostany's Research Publications